My husband keeps looking at me strangely and saying, “What have you done with my wife?”
I guess my personality is more….I don’t know…pleasant or something since I got my serotonin neutralization drops. He says I seem happier. I do feel like I have cleared a major hurdle. Like a mountain-sized hurdle.
Moving on to my next challenges…my hypertension, high blood sugar, and obesity. And hot flashes.
My doc suggested L-Arginine, in addition to CoQ10 and magnesium, to address the hypertension. I’ve taken magnesium glycinate for months, and CoQ10 off and on, so I didn’t think those two by themselves would make much of a difference, but I decided to try the L-Arginine this weekend. L-Arginine increases nitric oxide (NO), which acts as a vasodilator. I was hesitant to try it because one of my ongoing issues is hot flashes, which Ray Peat says occur relative to the effects of NO:
When doctors are talking about diseases of the heart and circulatory system, it’s common for them to say that estrogen is protective, because it causes blood vessels to relax and dilate, improving circulation and preventing hypertension. The fact that estrogen increases the formation of nitric oxide, a vasodilator, is often mentioned as one of its beneficial effects. But in the case of hot flashes, dilation of the blood vessels is exactly the problem, and estrogen is commonly prescribed to prevent the episodic dilation of blood vessels that constitutes the hot flash. Nitric oxide increases in women in association with the menopause (Watanabe, et al., 2000), and it is increased by inflammation, and hot flushes are associated with various mediators of inflammation, but, as far as I can tell, no one has measured the production of nitric oxide during a hot flash. Inhibitors of nitric oxide formation reduce vasodilation during hot flushes (Hubing, et al., 2010).
So I tried the L-Arginine, knowing full well it would increase NO, but still wanting to try. Well, it made my hot flashes worse and more frequent. So, done with that experiment. Currently my blood pressure is hovering around 140/90. Not good enough, but probably not going to kill me today.
Peat advocates maintaining higher blood sugar and using progesterone to address hot flashes. Still having a bottle of Progest E in my refrigerator, I decided maybe we should try this again. So I took a few drops before bed (10mg).